200937-17-3 Boc-D-Leu-OH•H2O

Biochemistry and Drug Discovery:
As an amino acid derivative, Boc-D-Leu-OH·H2O plays a crucial role in synthesizing biologically active peptides and proteins. Chemical modifications of this compound can lead to the development of novel drugs or drug candidates for treating various diseases. The unique properties of D-leucine may confer specific biological activities to the synthesized peptides or proteins.
Peptide Synthesis:
In solid-phase peptide synthesis, Boc-D-Leu-OH·H2O is a key amino acid monomer. Its N-terminal Boc protecting group allows amino acid ligation and deprotection under mild conditions, enabling the synthesis of peptide chains with specific sequences and functions.
Laboratory Research:
Boc-D-Leu-OH·H2O is commonly used in peptide synthesis and protein structure studies. By combining it with other amino acid monomers, various peptide sequences can be synthesized to investigate protein-protein and protein-ligand interactions, as well as protein function and regulation mechanisms.
Peptide Reagents and Synthetic Auxiliaries:
Boc-D-Leu-OH·H2O can serve as a protective agent or condensing agent in peptide synthesis, improving the efficiency and purity of the peptide synthesis process. Additionally, it can be used as a peptide reagent for peptide labeling, modification, and detection.
Asymmetric Synthesis:
Due to the chiral nature of D-leucine, Boc-D-Leu-OH·H2O has potential applications in asymmetric synthesis. By combining it with other chiral molecules, peptides and proteins with specific stereoconfigurations can be synthesized to study the impact of chirality on biological activities.