29022-11-5 Fmoc-Gly-OH

29022-11-5 Fmoc-gly-OH is one of intermediates of Triptorelin. Triptorelin, also called Triptorelin Acetate Injection, is a synthetic decapeptide analog of gonadotropin-releasing hormone (GnRH), but it is more active than natural GnRH, and regulates the levels of luteinizing hormone (LH), follicle stimulating hormone (FSH), testosterone (T), and estradiol (E2) in the blood of the human body, and has been used for various purposes. The active ingredient of Treprostinil is a synthetic analog of gonadotropin-releasing hormone (GnRH), also known as tryptophan, dafylline, dabigatran, gonadorelin, an antitumor drug with the same pharmacological effects as goserelin and buserelin, with the structural improvement of the natural molecular structure of the sixth levo-glycine is replaced by dextropro-tryptophan, which results in a more pronounced pro-active effect and a longer plasma half-life, and higher efficacy. Higher potency. After intramuscular injection, the pituitary gland is initially stimulated to release luteinizing hormone (LH) and chemicalbook follicle stimulating hormone (FSH). When the pituitary gland enters a phase of inappropriateness after prolonged stimulation, the release of gonadotropins decreases, thus lowering the sex hormones to depot levels. The above effects are reversible. Subcutaneous administration is rapidly absorbed, with a Tmax of 15 min and a maximum effect of 1 h. Sustained-release preparations for intramuscular injection can maintain efficacy for more than 28 d. Clinically, it is mainly used for the treatment of endometriosis, hormone-dependent prostate cancer, breast cancer, children's true precocious puberty, and can also be used for assisted reproduction techniques.