294855-91-7 Pal-Glu(OSU)-OH

Pal-Glu(OSU)-OH, also known as the liraglutide side chain, is an important chemical compound with a wide range of applications across various fields.

Firstly, in the fields of bioscience and medicine, Pal-Glu(OSU)-OH is utilized as a side chain for glucagon-like peptide-1 (GLP-1) receptor agonists. GLP-1 receptor agonists play a crucial role in the research of type 2 diabetes. By binding to the endogenous metabolic hormone GLP-1, these agonists stimulate insulin secretion and inhibit glucagon secretion, thereby aiding in the control of blood sugar levels. Consequently, Pal-Glu(OSU)-OH holds significant value in the development of therapeutics for diabetes.

Secondly, Pal-Glu(OSU)-OH is also used as a raw material for long-acting polypeptide drugs. Its unique chemical properties enable it to participate in the construction of peptide structures with specific biological activities, offering new possibilities for drug design and development. These polypeptide drugs have potential applications in the treatment of various diseases.

Moreover, Pal-Glu(OSU)-OH can be employed in the preparation of other compounds with specific functions. Due to its functional groups and reactive properties, it serves as a key intermediate in the synthesis of complex molecules, further expanding its applications in chemistry, materials science, and other related fields.