66638-37-7 Boc-N-Me-L-Tyr(tbu)-OH

Peptide Synthesis:
Boc-N-Me-L-Tyr(Tbu)-OH is a protected amino acid commonly used in solid-phase peptide synthesis (SPPS) and other peptide synthesis methods. With both the N-terminal and the side-chain hydroxyl groups protected, it maintains stability during peptide chain elongation, avoiding unwanted side reactions.
After the peptide chain synthesis is complete, the protecting groups can be removed under appropriate conditions, exposing the free amino and hydroxyl groups, thereby yielding the desired peptide or protein.
Protein Engineering:
In protein engineering, this protected amino acid can be used for site-specific modification of proteins. By reacting Boc-N-Me-L-Tyr(Tbu)-OH with specific sites on a protein, a methylated tyrosine residue can be introduced, altering the protein's properties and function.
Drug Design and Development:
Methylated tyrosine may exhibit specific biological activities or pharmacokinetic properties in certain drug designs. By using Boc-N-Me-L-Tyr(Tbu)-OH as a building block, researchers can explore the potential therapeutic efficacy and pharmacological properties of drug molecules containing methylated tyrosine.
Biochemical and Biological Research:
In biochemical and biological research, this protected amino acid can serve as a tool compound to study the role of methylated tyrosine in protein interactions, signal transduction, enzyme activity, and other aspects.
Bioconjugation and Labeling:
The methyl and protected hydroxyl groups of Boc-N-Me-L-Tyr(Tbu)-OH make it an ideal choice for bioconjugation and labeling reactions. By removing the protecting groups and reacting with other molecules or biologically active substances, labeled molecules with specific biological activities can be prepared.