84000-07-7 Fmoc-L-N-Me-Ala-OH

Peptide Synthesis: Fmoc-L-N-Me-Ala-OH serves as a building block in solid-phase peptide synthesis. The Fmoc (9-fluorenylmethoxycarbonyl) group is a widely used protecting group that allows for controlled and specific coupling reactions during peptide chain elongation. The L-N-Me-Ala moiety introduces a specific amino acid with modified chemical properties that can lead to peptides with unique biological activities.

Biological Activity Studies: The presence of the N-methyl group in Fmoc-L-N-Me-Ala-OH alters the biological properties of the alanine residue, potentially conferring novel bioactivities to the peptides containing it. Therefore, this compound can be used to investigate biological functions, such as protein-protein interactions, enzyme inhibition, or receptor binding, in vitro or in cellular models.

Drug Design and Development: Peptides have gained significant interest in drug design due to their high specificity and biocompatibility. The introduction of modified amino acids like Fmoc-L-N-Me-Ala-OH can enhance the stability, solubility, or biological activity of peptides, making them promising candidates for therapeutic applications. Researchers can use this compound to screen for potential drug leads or to optimize the pharmacological properties of existing peptide-based drugs.

Structural and Conformational Studies: The unique chemical properties of Fmoc-L-N-Me-Ala-OH can also be exploited in structural biology studies. By incorporating this amino acid derivative into peptides, researchers can investigate how modifications to the amino acid sequence affect the conformational preferences, stability, and interactions of these peptides with other biomolecules.