88574-06-5 Fmoc-6-AMINOHEXANOIC ACID

Solid-phase peptide synthesis (SPPS): 88574-06-5 Fmoc-6-AMINOHEXANOIC ACID is frequently used in SPPS to introduce a six-carbon linker between the resin and the peptide sequence. This linker can provide flexibility and space between peptide moieties, allowing for enhanced interactions with target molecules in certain bioconjugates or peptide modifications.

Peptide modification and labeling: The hexanoic acid side chain can serve as a linker for attaching various functional groups or labels to peptides. This can include fluorescent dyes, biotin, or other moieties used for labeling peptides for imaging studies, affinity purification, or other biochemical assays.

Stapled peptides: 88574-06-5 Fmoc-6-AMINOHEXANOIC ACID can be used to synthesize stapled peptides, which are modified peptides stabilized by a cross-linking bridge. These stapled peptides often exhibit improved protease resistance, cell permeability, and binding affinity compared to their linear counterparts. The hexanoic acid side chain can be utilized as part of the stapling moiety.

Peptide mimetics: By incorporating 88574-06-5 Fmoc-6-AMINOHEXANOIC ACID into peptide sequences, researchers can introduce structural modifications that mimic the conformational properties of natural peptides. This can lead to the development of peptide-based therapeutics with enhanced stability, bioavailability, and specificity.

Drug delivery systems: The hexanoic acid side chain can be utilized to attach peptides to drug delivery vehicles or carriers, such as nanoparticles or liposomes. This conjugation strategy can enhance the targeted delivery of therapeutic peptides to specific tissues or cells.